Clinical Trials in Peripheral Vascular Disease

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Clinical trials in peripheral vascular disease: pipeline and trial designs: an evaluation of the ClinicalTrials.gov database.

BACKGROUND Tremendous advances have occurred in therapies for peripheral vascular disease (PVD); until recently, however, it has not been possible to examine the entire clinical trial portfolio of studies for the treatment of PVD (both arterial and venous disease). METHODS AND RESULTS We examined interventional trials registered in ClinicalTrials.gov from October 2007 through September 2010 (...

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Amputations in peripheral vascular disease.

Until the cause of organic occlusive vascular diseases is definitely estab­ lished, and prophylactic measures taken to prevent them; until lipid metabolism can be controlled to pre­ vent atherosclerotic plaques from ad­ hering to the intima of arteries; until thrombosis and embolism can be pre­ vented and it will be routine to excise arterial segments and replace them with homografts or plastic...

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Problems in Peripheral Vascular Disease

THIS is the English edition (by Dr Gunn) of a detailed, step-by-step instruction manual for the full physical examination of patients. It is the product of Dr Lordwick and members of the "Skills Laboratory" of the Medical School in the University of Limburg, Holland. The basic aim is that students should acquire the medical skills of patient examination in a systematic and reasonably standardiz...

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Angioplasty in peripheral vascular disease.

Percutaneous revascularization as an alternative to surgery in the management of peripheral vascular disease was first described in 1964 but gained little acceptance.' In 1974 the development of a doublelumen balloon catheter by Gruntzig and others made the technique a much more practical and effective one that has subsequently gained widespread acceptance.2 At first it was used in the peripher...

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Peripheral vascular disease.

There is little doubt that one of the greatest advances in the field of peripheral arterial disease was our ability to visualize problems wherever they occurred. This was possible because of the development of arteriography. One of the dramatic developments that made this possible was the observation by Forsmann1 in 1929 that a catheter could be threaded through a peripheral vein into the right...

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ژورنال

عنوان ژورنال: Circulation

سال: 2014

ISSN: 0009-7322,1524-4539

DOI: 10.1161/circulationaha.114.011021